Radiofrequency Ablation vs. VenaSeal: Which Varicose Vein Treatment Is Better?

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Dr. Darryl Lim

Vascular and Endovascular Surgeon | Singapore

Radiofrequency ablation (RFA) and VenaSeal are both excellent treatments for varicose veins, but the right choice depends on individual factors. RFA uses heat energy to close veins, while VenaSeal relies on a medical adhesive. RFA has over 20 years of clinical success with a 90–98% five-year success rate, whereas VenaSeal, though newer, has a comparable 94–95% success rate. RFA is more cost-effective but requires compression stockings, while VenaSeal offers a faster recovery with minimal post-procedure care. Both are safe and effective, and a vascular specialist can help determine the best option for you.

The short answer: Both are excellent — but the right choice depends on your needs.

Radiofrequency ablation (RFA) and VenaSeal are two of the most popular minimally invasive vein surgery options for treating varicose veins. They both work by closing off faulty veins to redirect blood flow to healthier ones, but they do so in different ways. Choosing between the two often comes down to your anatomy, lifestyle, and medical considerations.

Let’s break down the differences to help you decide which might be the best vein treatment for you.

How Do These Treatments Work?

Radiofrequency Ablation (RFA) uses heat energy to close off the problem vein. A thin catheter is inserted into the vein, and radiofrequency energy is applied to seal it shut. It’s a tried-and-tested method with excellent long-term results.

VenaSeal is a newer technique that uses a medical adhesive (a type of bio-glue) to seal the vein shut. Instead of heat, it relies on a safe, cyanoacrylate-based glue to close the vein from the inside, with no need for thermal energy.

Key Differences Between RFA and VenaSeal

FeatureRadiofrequency Ablation (RFA)VenaSeal
TechniqueThermal (heat-based)Medical adhesive (glue)
AnaesthesiaLocal anaesthesia or light general anaesthesiaUsually requires only local anaesthesia
Compression StockingsWorn for 1–2 weeks after the procedureOften not required
Pain/DiscomfortMild discomfort or bruising commonMild discomfort; no heat application
Recovery TimeBack to normal in 24–48 hoursBack to normal in 24–48 hours
Post-Procedure CareSome aftercare needed (stockings, activity restrictions)Minimal post-procedure care
SuitabilityExcellent for most patientsNot ideal for very superficial veins or those prone to adhesive reactions
RisksBruising, tenderness, nerve injury, skin irritationHypersensitivity, allergic reaction, nerve injury, local skin changes
Long-Term DataOver 20 years of clinical use with robust long-term outcomesNewer, with growing but limited long-term data (under 10 years)
Success Rate90–98% at 5 yearsApproximately 94–95% at 5 years
CostTypically more cost-effectiveGenerally more expensive due to adhesive material

Effectiveness and Long-Term Results

When comparing radiofrequency ablation vs VenaSeal, both offer strong long-term closure rates and symptom relief.

  • RFA has been in use for over two decades and boasts success rates of around 90–98% in five years. It’s considered the gold standard for thermal vein treatments.
  • VenaSeal is newer but shows similarly high success rates — approximately 94–95% — in clinical trials and real-world use.

Both are considered safe, effective options for minimally invasive vein surgery, and recurrence rates are low when performed by experienced hands.

Doctors doing vein surgery procedure on patients leg

Pros and Cons at a Glance

Radiofrequency Ablation (RFA)VenaSeal
Pros– Proven long-term outcomes
– Widely available
– Cost-effective
– Suitable for most vein types
– No compression stockings needed (in most cases)
– Minimal downtime
– Very little post-op discomfort
– No thermal injury risk
Cons– Requires compression stockings
– May cause bruising or tenderness
– Not ideal for very small or tortuous veins
– Minor risk of nerve injury
– Higher cost
– Not suitable for very superficial or tortuous veins
– Risk of hypersensitivity or allergic reaction
– Limited long-term data (under 10 years)
– Possible local irritation in superficial veins

So, Which One Is Better?

There’s no single “best vein treatment” — it really depends on your individual case. If you’re looking for a proven, cost-effective option with strong long-term data, radiofrequency ablation is an excellent choice. If you’re after a more comfortable recovery and want to avoid compression stockings, VenaSeal may be the better fit.

Some patients may even benefit from a combination of treatments, depending on how many veins are affected and their specific anatomy.

Final Thoughts

Both RFA and VenaSeal offer safe, effective, and minimally invasive solutions for treating varicose veins. The key is choosing the treatment that best fits your vein condition, lifestyle, and personal preferences.

Dr Darryl Lim is a vascular surgeon in Singapore with experience in both RFA and VenaSeal procedures. If you’re considering treatment for varicose veins, he can help guide you through your options and tailor a plan that’s right for you.

FAQ

Is VenaSeal better than radiofrequency ablation?
Both are highly effective. VenaSeal offers a faster recovery, but RFA has a longer track record. The best choice depends on your veins and your goals.

Which vein treatment is less painful?
VenaSeal is generally associated with less post-procedure discomfort, as it doesn’t use heat.

Do I have to wear compression stockings after treatment?
After RFA, yes — usually for 1 to 2 weeks. With VenaSeal, compression stockings are often not required.

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Dr. Darryl Lim

Dr. Darryl Lim

Vascular and Endovascular Surgeon | Singapore

Dr. Darryl Lim is a Senior Consultant Vascular and Endovascular Surgeon at the Novena Vascular and Varicose Vein Centre in Singapore. Before this role, he served as the Director of the Vascular Unit at Changi General Hospital and as a Service Chief at the Singhealth-Duke NUS Vascular Centre. Under his tenure, Changi General Hospital’s Vascular Unit was recognized as a regional centre of excellence.

Dr. Lim has a strong commitment to training emerging interventionalists and enhancing the capabilities of vascular units in Southeast Asia. He is regularly invited to travel to regional units to conduct live case workshops and to speak at international conferences.

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